师资队伍

  • 姓名:程晓非
  • 性别:
  • 职称:教授
  • 硕、博导:博导
  • 学科领域:植物保护学
  • 研究方向:植物病毒学
  • 办公地点:农学楼605室
  • 办公电话:
  • 电子邮件:xfcheng@neau.edu.cn

个人简介

学习经历:

2000年9月-2004年7月,安徽大学生命科学学院生物科学本科毕业,获理学学士学位

2004年9月-2007年07月,云南农业大学植物保护学院植物病理学硕士毕业,获农学硕士学位(与云南省农科院生物技术与种质资源研究所联合培养)

2007年9月-2010年6月,浙江大学农业与生物技术学院生物化学与分子生物学博士毕业,获理学博士学位

2008年8月-2009年8月,美国Samuel Roberts Noble Foundation国家留学基金委公派联合培养博士

2013年9月-2016年9月,加拿大农业部London Research and Development Centre,博士后

2013年10月-2017年2月,加拿大农业部London Research and Development Centre,研究科学家

作经历:

2010年08月-2013年09月,杭州师范大学生命与环境科学学院,助理研究员;

2013年09月-2017年09月,杭州师范大学生命与环境科学学院,副研究员;

2017年10月-至今,东北农业大学农学院,教授

教学工作

讲授《分子生物学》、《分子生物学实验》本科生课程;讲授《分子生物学技术(英文授课)》、《SCI科技论文写作》研究生课程。

科研项目

1、植物病毒学(32022071),国家自然科学基金优秀青年项目,2021年1月-2024年12月;

2、苜蓿花叶病毒对大豆的致病机制及大豆抗性资源挖掘研究,中央支持地方高校改革发展资金人才培养支持计划项目,2019年12月-2021年12月;

3、马铃薯X病毒编码的TGB2蛋白耦合病毒复制和运动的分子机理研究(31671998),国家自然科学基金面上项目,2017年1月-2020年12月;

4、植物病毒抑制寄主系统性获得免疫的分子机理及应用研究(ZD2018002),黑龙江省自然科学基金重点项目,2018年1月-2019年12月;

5、大豆花叶病毒致病性差异的分子机制研究(2018QD0002),黑龙江省科技厅留学回国择优启动项目,2019年1月-2020年12月;

6、NSERC Visiting fellowship,加拿大NSERC,2013年9月-2016年9月;

7、利用人工锌指蛋白进行多价抗双生病毒的研究(31101417),国家自然科学基金青年项目,2012年1月-2014年12月;

8、基于人工锌指核酸酶抗双生病毒体系的建立与评价(Y3110175),浙江省自然科学基金一般项目,2012年1月-2014年12月;

9、中美联合培养博士计划,国家留学基金委员会,2008年7月-2009年7月。

论文著作

1.Siqi Yang, Ye Liu, Xiaoyun Wu, Xiaofei Cheng*, Xiaoxia Wu*. Synonymous codon pattern of cowpea mild mottle virus sheds light on its host adaptation and genome evolution. Pathogens, 2022, 11(4): 419.

2.Xue Jiang, Yameng Luan, Mengzhu Chai, Yingshuai Yang, Yuting Wang,Wenjia Deng, Yonggang Li, Xiaofei Cheng*, Xiaoyun Wu*. The N-terminal α-helix of potato virus X-encoded RNA-dependent RNA polymerase is required for membrane association and multimerization. Viruses, 2022, 14: 1907.

3.Xiaoyun Wu, Mengzhu Chai, Jiahui Liu, Xue Jiang, Yingshuai Yang, Yushuang Guo, Yong Li*, Xiaofei Cheng*. Turnip mosaic virus manipulates DRM2 expression to regulate host CHH and CHG methylation for robust infection. Stress Biology, 2022, 2: 29.

4.Yameng Luan, Lili Zhang, Ting Sun, Xue Jiang, Xiaoyun Wu*, Xiaofei Cheng*. First report of a secovirus associated with mountain celery chlorotic spot disease in Heilongjiang, China. Plant Disease, 2022, 106 (4): 1311.

5.Xiu Su, Xiang Zhou, Yuan Li, Liangjin Ma, Xiaofei Cheng*, Kai Guo*. First report of bean common mosaic virus infecting heavenly bamboo (Nandina domestica) in China. Plant Disease, 2022, 106(3): 1079.

6.Jiahui Liu, Ye Liu, Yue Fang, Lili Zhang, Kaixin Yu, Xiaoyun Wu, Xiaofei Cheng*. Evaluation of potato virus X resistance in potato cultivars and identification of an innate immunity-independent resisantce phenotype. Phytopathology Research, 2021, 3:21. DOI: 10.1186/s42483-021-00099-6

7.Xiaofei Cheng, Yameng Luan, Xiaoyun Wu. Plant nonhost resistance against viruses: current status and future prospects. In: Guar RK, Khurana SMP, Sharma P, Hohn T eds. Plant virus-host interaction-molecular approaches and viral evolution (second edition). Academic press. London, UK. 2021, 45-57.

8.Xiaofei Cheng*, Yameng Luan, Aiming Wang. In vivo detection of double-stranded RNA by dRBFC assay. In: Wang A, Li Y eds. Plant Virology: Methods and Protocols, Methods in Molecular Biology, 2400, 1-9.

9.Xiaoyun Wu, Xiaofei Cheng*. Intercellular movement of plantRNA viruses: Targeting replication complexes to the plasmodesma for bothaccuracy and efficiency. Traffic, 2020, 1-12. DOI: 10.1111/tra.12768.

10.Xiaoyun Wu, Jiahui Liu, Xiaofei Cheng*. First report ofCamellia japonica associated emaravirus 1 associated with camellia leafringspot and flower color-breaking disease in China. Plant Disease, 2020, DOI:10.1094/PDIS-03-20-0657-PDN.

11.Xinyang Che, Xue Jiang, Xinlei Liu, Xiaoyan Luan, Qi Liu, XiaofeiCheng*, Xiaoyun Wu*. First report of Alfalfa mosaic virus on soybean inHeilongjiang, China. Plant Disease, 2020, 104 (11): 3085.

12.Mengzhu Chai, Xiaoyun Wu, Jiahui Liu, Yue Fang, Yameng Luan, XiaoyanCui, Xueping Zhou, Aiming Wang, Xiaofei Cheng*. P3N-PIPO interacts withP3 via the shared N-terminal domain to recruit viral replication vesicles forcell-to-cell movement. Journal of Virology, 2020, 94(8): e01898-19.

13.Ruonan Zhang, Xiaoyun Wu, Xue Jiang, Xiaoxia Wu, Xiaoyan Luan, XiaofeiCheng*. Molecular characterization of Common bean curly stunt virus: anovel recombinant geminivirus in China. Archives of Virology, 2020, 165:257-260.

14.刘佳慧,刘野,张若男,武晓云,刘琦,程晓非*.山茶褪绿矮缩伴随病毒杭州分离物的序列和进化分析.植物病理学报,2020,50(1):117-121.

15.Jiahui Liu, Lili Zhang, Feifei Xu, Mengzhu Chai, Xiaodong Wu, UnsongKim, Dianqiu Lv, Xiaoyun Wu, Xiaoxia Wu, Xiaofei Cheng*. Molecularanalysis of a divergent isolate of potato virus H from potato reveals novelevolutionary feature of Carlaviruses. Canadian Journal of Plant Pathology,2020, 42: 116-124.

16.Xiaoyun Wu, Jiahui Liu, Mengzhu Chai, Jinhui Wang, Dalong Li, Aiming Wang,Xiaofei Cheng*. ThePotato virus XTGBp2 protein plays dual functional roles in viral replication and movement. Journal of Virology, 2019, 93: e01635-18.

17.Xiaoyun Wu, Adrian Valli, Juan Antonio Garcia, Xueping Zhou,Xiaofei Cheng*. The tug-of-war between plants and viruses: great progress and many remaining questions. Viruses, 2019, 11: 203.

18.Ruonnan Zhang, Xiaoyun Wu, Xue Jiang, Xiaoxia Wu, Xiaoyan Luan,Xiaofei Cheng*. Molecular characterization ofCommon bean curly stunt virus: a novel recombinant geminivirus in China. Archives of Virology, 2019, DOI: 10.1007/ s00705-019-04473-w.

19.Jiahui Liu, Lili Zhang, Feifei Xu, Mengzhu Chai, Xiaodong Wu, Unsong Kim, Dianqiu Lv, Xiaoyun Wu, Xiaoxia Wu,Xiaofei Cheng*. Molecular analysis of a divergent isolate ofPotato virus Hfrom potato reveals novel evolutionary feature of carlaviruses.Canadian Journal of Plant Pathology, 2019, DOI: 10.1080/07060661.2019.1625947.

20.Palmiro Poltronieri, Alexandre Brutus, Ida B. Reca, Fedra Francocci,Xiaofei Cheng, Egidio Stigliano. Engineering plant leucine rich repeat-receptors for enhanced pattern-triggered immunity (PTI) and effector-triggered immunity (ETI). In: Poltronieri P, Hong YG eds. Applied Plant Biotechnology for Improving Resistance to Biotic Stress. Academic Press (Oxford, UK), 2019. pp. 1-31.

21.刘佳慧,刘野,张若男,武晓云,刘琦,程晓非*.山茶褪绿矮缩伴随病毒杭州分离物的序列和进化分析.植物病理学报,2019,DOI: 10.13926/j.cnki.apps.000407

22.Tong Han, Qiushi Hou,Xiaofei Cheng, Juan Antonio Garci, Adrian Valli, Song Zhang, Mengji Cao, Caixia Yang. Complete genome sequence of a novel member of the familyPotyviridaeisolated fromPhellodendron amurenserupr. in Liaoning, China. Archives of Virology, 2019, 164: 1705-1709.

23.Xiaoyun Wu, Qi Liu, Mengzhu Chai, Lili Zhang,Xiaofei Cheng*, First report ofPotato aucuba mosaic viruson potato in China. Plant Disease, 2018 102(12): 2671.

24.Xiaodong Wu,Xiaofei Cheng*, Wenbin Li*. First report of natural infection ofWatermelon mosaic virusonLagerstroemia indicain China. Plant Disease, 2018, 102(5): 1048.

25.Xiaodong Wu, Xiaoyun Wu, Wenbin Li,Xiaofei Cheng*. Molecular characterization of a divergent strain ofCalla lily chlorotic spot virusinfecting celtuce (Lactuca sativa var. augustana) in China. Archives of Virology, 2018, 163(5): 1375-1378.

26.Xiaofei Cheng+, Ruyi Xiong+, Yinzi Li, Fangfang Li, Xueping Zhou, Aiming Wang*. Sumoylation of theTurnip mosaic virusRNA polymerase promotes viral infection by counteracting the host NPR1-mediated immune response. Plant Cell, 2017, 29(3): 508-525.

27.Xiaofei Cheng, Aiming Wang*. The potyviral silencing suppressor protein VPg mediates degradation of SGS3 via ubiquitination and autophagy pathways. Journal of Virology, 2017, 91(1): e01478-16.

28.Xiaofei Cheng, Aiming Wang*. Multifaceted defense and counter-defense in co-evolutionary arms race between plants and viruses. Communicative & Integrative Biology, 2017, 10:4, e1341025.

29.Linyun Chen,Xiaofei Cheng, Jianyu Cai, Linlin Zhan, Xiaoxia Wu, Qi Liu, Xiaoyun Wu*. Multiple virus resistance using artificial trans-acting siRNAs. Journal of Virological Methods, 2016, 228: 16–20.

30.Xiaofei Cheng, Ping Deng, Hongguang Cui, Aiming Wang*. Visualizing double-stranded RNA distribution and dynamics in living cells by dsRNA binding-dependent fluorescence complementation. Virology, 2015, 485: 439-451.

31.Xiaofei Cheng+, Fangfang Li+, Jianyu Cai, Wei Chen, Nan Zhao, Yuqiang Sun, Yushuang Guo, Xiulin Yang, Xiaoyun Wu*. Artificial TALE as a convenient protein platform for engineering broad-spectrum resistance to begomoviruses. Viruses, 2015, 7: 4772-4782.

32.Yilun Wang+,Xiaofei Cheng+, Xiaoxia Wu, Aiming Wang, Xiaoyun Wu*. Characterization of complete genome and small RNA profile ofPagoda yellow mosaic associated virus, a novel badnavirus in China. Virus Research, 2014, 188: 103-108.

33.Xiaofei Cheng, Nasar Virk, Huizhong Wang. 2014. Impact of the host on plant virus evolution. In: Gaur RK, Hohn T, Sharma P. eds. Plant Virus-Host Interaction: Molecular approaches and viral evolution. Academic Press (Oxford), pp. 359-371.

34.Wei Chen, Yongsheng Qian, Xiaoyun Wu, Yuqiang Sun, Xiaoxia Wu,Xiaofei Cheng*. Inhibiting replication of begomoviruses using artificial zinc finger nucleases that target viral-conserved nucleotide motif. Virus Genes, 2014, 48:494-501.

35.Xiaofei Cheng*, Nasar Virk, Wei Chen, Shuqing Ji, Shuxian Ji, Yuqiang Sun, Xiaoyun Wu*. CpG usage in RNA viruses: data and hypotheses. Plos One, 2013, 8(9): e74109.

36.Xiaofei Cheng, Wei Chen, Zhenhua Zhou, Junjun Liu, Huizhong Wang*. Functional characterization of a novel tropinone reductase-like gene inDendrobium nobileLindl. Journal of Plant Physiology, 2013, 170: 958-964.

37.WeiChen+,Xiaofei Cheng+, Zhenhua Zhou, Junjun Liu, Huizhong Wang*. Molecular cloning and characterization of a tropinone reductase fromDendrobium nobileLindl. Molecular Biology Reports, 2013, 40: 1145-1154.

38.Xiaofei Cheng*, Xiaoyun Wu, Huizhong Wang, Yuqiang Sun, Yongsheng Qian, Lu Luo. High codon adaptation inCitrus tristeza virusto its citrus host. Virology Journal, 2012, 9: 113.

39.Xiaoyun Wu, Haitao Ding, Liping Ke, Yueyong Xin,Xiaofei Cheng* Characterization of an acid-resistant glucose 1-dehydrogenase fromBacillus cereusvar. mycoides, Romanian Biotechnological Letters, 2012, 17(4): 7540-7548.

40.Xiaofei Cheng, Xiaoqiang Wang, Jianxiang Wu, Rob W. Briddon, Xueping Zhou*.βC1 encoded byTomato yellow leaf curl China betasatelliteforms multimeric complexes in vitro and in vivo. Virology, 2011, 409: 156-162.

41.Xiaofei Cheng, Jianxiang Wu, Xinyin Ma, Huafu Fu, Xiaoyun Wu*. First report ofCitrus tristeza virusinCitrus changshanensiscv. Huyou in Zhejiang, China. Journal of plant Pathology, 2011, 93(s4): 68.

42.Xiaoyun Wu, Jianxiang Wu,Xiaofei Cheng*. First report of natural infection ofBroad bean wilt virus-2onLactuca indica. Journal of Plant Pathology, 2010, 92(s4): 119.

43.Xiaofei Cheng, Jiahong Dong, Qi Fang, Ming Ding, Jenifer McBeatch, Zhongkai Zhang*. Detection ofImpatiens necrotic spot virusinfectingPhalaenopsisin Yunnan. Journal of Plant Pathology, 2010, 92(2): 545.

44.Jiahong Dong+,Xiaofei Cheng+, Yueyan Yin, Qi Fang, Ming Ding, Tingting Li, Lizhen Zhang, Xiaoxia Su, Jenifer McBeath, Zhongkai Zhang*. Characterization ofTomato zonate spot virus, a new tospovirus species in China. Archives of Virology, 2008, 153(5): 855-864.

45.程晓非,董家红,方琦,李婷婷,丁铭,张仲凯.从云南蝴蝶兰上检测到番茄斑萎病毒属病毒.植物病理学报,2008,38(1):31-34.

 

其他成果

专利:

1、一种苜蓿花叶病毒的侵染性克隆、重组农杆菌及构建方法,ZL202010461785.8,2018。

2、一种马铃薯X病毒弱毒疫苗及其制备方法与应用,ZL201811376177.6,2018。

3、蓟马昆虫室内饲养罐(排名第4),ZL200520100047,2007。

获奖:

1、加拿大NSERCVisiting FellowshipAward(排名第1),2013

2、东北农业大学“东农学者”学术骨干称号(排名第1),2017

3、东北农业大学青年教师教学技能大赛三等奖(排名第1),2019;

4、东北农业大学“陈徽凤”奖教金(排名第1),2019;

5、国家优青,2020

6、东北农业大学“五四”青年奖章,2020

7、黑龙江省委教育工委优秀共产党员,2021

8、东北农业大学突出贡献奖,2022